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Information about Precose.

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use this medication only for the indication prescribed.

Precose was statistically significantly different from placebo at all doses with respect to effect on one-hour postprandial plasma glucose.

Your medication needs may change if you become sick or injuredif you have a serious infectionor if you have any type of surgeryDo not change your dose or stop taking acarbose without first talking to your doctor.

It may be harder to control your blood sugar when your body is stressedsuch as due to feverinfectioninjuryor surgeryConsult your doctor because this may require a change in your treatment planmedicationsor blood sugar testing.

In contrast to sulfonylureasPrecose does not enhance insulin secretionThe antihyperglycemic action of acarbose results from a competitivereversible inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucoside hydrolase enzymesPancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestinewhile the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharidestrisaccharidesand disaccharides to glucose and other monosaccharides in the brush border of the small intestineIn diabetic patientsthis enzyme inhibition results in a delayed glucose absorption and a lowering of postprandial hyperglycemia.

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