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During or immediately after the administrationadequate amounts of fluid should be ingested or infused to force diuresis in order to reduce the risk of urinary tract toxicityThereforecyclophosphamide should be administered in the morning.

A very serious allergic reaction to this drug is unlikelybut seek immediate medical attention if it occursSymptoms of a serious allergic reaction may includerashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.

CongenitalFamilial and Geneticintra-uterine deathfetal malformationfetal growth retardationfetal toxicityincluding myelosuppressiongastroenteritis

Renal and Urinaryrenal failurerenal tubular disorderrenal impairmentnephropathy toxichemorrhagic cystitisbladder necrosiscystitis ulcerativebladder contracturehematurianephrogenic diabetes insipidusatypical urinary bladder epithelial cells.

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