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4Because of the advantages of ADTit may be desirable to try patients on this form of therapy who have been on daily corticoids for long periods of timeegpatients with rheumatoid arthritisSince these patients may already have a suppressed HPA axisestablishing them on ADT may be difficult and not always successfulHoweverit is recommended that regular attempts be made to change them overIt may be helpful to triple or even quadruple the daily maintenance dose and administer this every other day rather than just doubling the daily dose if difficulty is encounteredOnce the patient is again controlledan attempt should be made to reduce this dose to a minimum.

How are patients monitoredPatients will usually have scheduled meetings with their healthcare provider while they are being treated with prednisoneBlood may be drawn to check levels of blood cells and to monitor functions of some organ systemssuch as the kidneys or liverPatients may also undergo physical examinationsscans or other measures to assess side effects and response to therapyPatients may also have their blood sugar and electrolytepotassiumlevels monitored.

2ADT is a therapeutic technique primarily designed for patients in whom long-term pharmacologic corticoid therapy is anticipated.

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