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Stop taking flutamide and seek emergency medical attention if you experience an allergic reactiondifficulty breathingclosing of your throatswelling of your lipstongueor faceor hives

Serum transaminase levels should be measured prior to starting treatment with flutamideFlutamide is not recommended in patients whose ALT values exceed twice the upper limit of normalSerum transaminase levels should then be measured monthly for the first 4 months of therapyand periodically thereafterLiver function tests also should be obtained at the first signs and symptoms suggestive of liver dysfunctionegnauseavomitingabdominal painfatigueanorexiaflu-likesymptomshyperbilirubinuriajaundiceor right upper quadrant tendernessIf at any time a patient has jaundiceor their ALT rises above 2 times the upper limit of normalflutamide should be immediately discontinued with close follow-up of liver function tests until resolution.

Important Limitations of Use The information provided above on the drug you have selected is provided for your information only and is not a substitute for consultation with an appropriate medical doctorWe are providing this information solely as a courtesy andas suchit is in no way a recommendation as to the safetyefficacy or appropriateness of any particular drugregimendosing schedule for any particularcancercondition or patient nor is it in any way to be considered medical advicePatients should discuss the appropriateness of a particular drug or chemotherapy regimen with their physician.

DRUG INTERACTIONSThe effects of some drugs can change if you take other drugs or herbal products at the same timeThis can increase your risk for serious side effects or may cause your medications not to work correctlyThese drug interactions are possiblebut do not always occurYour doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.To help your doctor or pharmacist give you the best carebe sure to tell your doctor or pharmacist about all the products you useincluding prescription drugsnonprescription drugsand herbal productsbefore starting treatment with this productWhile using this productdo not startstopor change the dosage of any other medicines you are using without your doctor’s approval.Some of the products that may interact with this drug includetestosteronepatchgelinjectionanabolic steroidsincluding over-the-counter androgens/anabolics/testosterone precursorsDHEAwarfarin.This document does not contain all possible interactionsKeep a list of all the products you useShare this list with your doctor and pharmacist to lessen your risk for serious medication problems.

Your doctor will need to monitor your liver function with blood tests before starting treatment with flutamideevery month for the first 4 months of treatmentand periodically thereafter.

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