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Do not stop taking this medication without consulting your doctorSome conditions may become worse when this drug is suddenly stoppedYour dose may need to be gradually decreased.

Hyperkalemia has been reported in diabetic patients with the use of potassium-conserving agents even in the absence of apparent renal impairmentAccordinglyMAXZIDEtriamterene and hydrochlorothiazideshould be avoided in diabetic patientsIf it is employedserum electrolytes must be frequently monitored.

In patients requiring hydrochlorothiazide therapy and in whom hypokalemia cannot be risked therapy may be initiated with MAXZIDE-25 MGIf an optimal blood pressure response is not obtained with MAXZIDE-25 MGthe dose should be increased to two MAXZIDE-25 MG tablets daily asa single doseor one MAXZIDE tablet dailyIf blood pressure still is not controlledanother antihypertensive agent may be addedsee PRECAUTIONSDRUG INTERACTIONS

Calcium excretion is decreased by thiazidesPathological changes in the parathyroid gland with hypercalcemia and hypophosphatemia have been observed in a few patients on prolonged thiazide therapyThe common complications of hyperparathyroidism such as renal lithiasisbone resorptionand peptic ulceration have not been seenThiazides should be discontinued before carrying out tests for parathyroid function.

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