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If there is any indication of abnormality in the visual acuityvisual fieldcolor visionor retinal macular areassuch as pigmentary changesloss of foveal reflexor any visual symptomssuch as light flashes and streakswhich are not fully explainable by difficulties of accommodation or corneal opacitiesthe drug should be discontinued immediately and the patient closely observed for possible progressionRetinal changesand visual disturbancesmay progress even after cessation of therapysee ADVERSE REACTIONS

The dosage for adults may also be calculated on the basis of body weightthis method is preferred for infants and childrenA total dose representing 25 mg of base per kg of body weight is administered in three daysas follows:

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