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The main challenge with preventing malaria is that some species of mosquito in certain countries have become resistant to the commonly used drugs such as chloroqine and proguanilLariam was developed to overcome such resistance and so was deemed to be useful if travelling to countries where there is a type of malaria that is particularly difficult to treatBut no single medicine is effective against all malaria parasitesThe choice of a particular medicine depends on the sensitivity of the malaria parasites found in particular areas.

Patients should be managed by symptomatic and supportive care following LariammefloquineoverdoseThere are no specific antidotesMonitor cardiac functionif possible by ECGand neuropsychiatric status for at least 24 hoursProvide symptomatic and intensive supportive treatment as requiredparticularly for cardiovascular disturbances.

This list is not complete and many other drugs can interact with LariamThis includes prescription and over-the-counter medicinesvitaminsand herbal productsGive a list of all your medicines to any healthcare provider who treats you.

Howeveryour doctor may prescribe mefloquine to treat malaria even if you do have any of the conditions listed above.

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, valproic acid, carbamazepine, phenobarbital or phenytoin , the concomitant use of lariam may reduce seizure control by lowering the plasma levels of the anticonvulsant.

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